ムスカリン性アセチルコリン受容体M4治療薬市場:パイプラインレビュー(2020年上半期)

◆英語タイトル:Muscarinic Acetylcholine Receptor M4 - Pipeline Review, H1 2020
◆商品コード:GDATA20MY0974
◆発行会社(リサーチ会社):Global Markets Direct
◆発行日:2020年3月31日
◆ページ数:82
◆レポート言語:英語
◆レポート形式:PDF
◆納品方法:Eメール
◆調査対象地域:グローバル
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【レポートの概要】

Muscarinic Acetylcholine Receptor M4 – Pipeline Review, H1 2020
Summary

Muscarinic Acetylcholine Receptor M4 (CHRM4) pipeline Target constitutes close to 17 molecules. The latest report Muscarinic Acetylcholine Receptor M4 – Pipeline Review, H1 2020, outlays comprehensive information on the Muscarinic Acetylcholine Receptor M4 (CHRM4) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.

Muscarinic Acetylcholine Receptor M4 (CHRM4) – Muscarinic acetylcholine receptor M4 or cholinergic receptor muscarinic 4 (CHRM4) is a protein encoded by the CHRM4 gene. It mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical and Discovery stages are 1, 3, 2, 8 and 3 respectively. Report covers products from therapy areas Central Nervous System, Genetic Disorders, Mouth and Dental Disorders and Ophthalmology which include indications Alzheimer’s Disease, Schizophrenia, Psychosis, Amnesia, Amyotrophic Lateral Sclerosis, Angelman Syndrome, Anxiety Disorders, Cognitive Disorders, Cognitive Impairment, Cognitive Impairment Associated With Schizophrenia (CIAS), Depression, Fragile X Syndrome, Infantile Spasm (West Syndrome), Movement Disorders, Multiple Sclerosis, Neurology, Pain, Parkinson’s Disease, Presbyopia, Rett Syndrome, Sialorrhoea and Tuberous Sclerosis.

Furthermore, this report also reviews key players involved in Muscarinic Acetylcholine Receptor M4 (CHRM4) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

- The report provides a snapshot of the global therapeutic landscape for Muscarinic Acetylcholine Receptor M4 (CHRM4)
- The report reviews Muscarinic Acetylcholine Receptor M4 (CHRM4) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Muscarinic Acetylcholine Receptor M4 (CHRM4) targeted therapeutics and enlists all their major and minor projects
- The report assesses Muscarinic Acetylcholine Receptor M4 (CHRM4) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Muscarinic Acetylcholine Receptor M4 (CHRM4) targeted therapeutics

Reasons to Buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Muscarinic Acetylcholine Receptor M4 (CHRM4)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Muscarinic Acetylcholine Receptor M4 (CHRM4) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

【レポートの目次】

Table of Contents
List of Tables
List of Figures
Introduction
Global Markets Direct Report Coverage
Muscarinic Acetylcholine Receptor M4 (CHRM4) – Overview
Muscarinic Acetylcholine Receptor M4 (CHRM4) – Therapeutics Development
Products under Development by Stage of Development
Products under Development by Therapy Area
Products under Development by Indication
Products under Development by Companies
Muscarinic Acetylcholine Receptor M4 (CHRM4) – Therapeutics Assessment
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Muscarinic Acetylcholine Receptor M4 (CHRM4) – Companies Involved in Therapeutics Development
Anavex Life Sciences Corp
AstraZeneca Plc
Cerevel Therapeutics LLC
Karuna Therapeutics Inc
NeuroHealing Pharmaceuticals Inc
NeuroSolis Inc
Presbyopia Therapies LLC
Sosei Heptares
Suven Life Sciences Ltd
Muscarinic Acetylcholine Receptor M4 (CHRM4) – Drug Profiles
(aceclidine + tropicamide) – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Muscarinic Acetylcholine Receptor M4 (CHRM4) – Dormant Products
Muscarinic Acetylcholine Receptor M4 (CHRM4) – Discontinued Products
Muscarinic Acetylcholine Receptor M4 (CHRM4) – Product Development Milestones
Featured News & Press Releases
Feb 24, 2020: Anavex Life Sciences announces publication of foundational data for ANAVEX2-73 (blarcamesine) in multiple sclerosis (MS)
Feb 03, 2020: Anavex Life Sciences announces Fast Track Designation granted by U.S. FDA for ANAVEX2-73 (blarcamesine) clinical development program for the treatment of Rett Syndrome
Jan 27, 2020: Anavex Life Sciences announces achievement of enrollment target for the ANAVEX2-73 (blarcamesine) phase 2 Parkinson’s Disease Dementia (PDD) clinical trial
Jan 08, 2020: Anavex Life Sciences issued new U.S. patent for ANAVEX2-73 treatment of Neurodevelopmental Disorders including Rett Syndrome and Multiple Sclerosis
Dec 04, 2019: Anavex Life Sciences presents ANAVEX2-73 (blarcamesine) data at 12th Clinical Trials on Alzheimer’s Disease (CTAD) 2019 conference
Nov 19, 2019: Karuna Therapeutics’ schizophrenia drug passes Phase II trial
Nov 18, 2019: Karuna Therapeutics announces KarXT met primary endpoint in Phase 2 Clinical Trial of Acute Psychosis in Patients with Schizophrenia
Nov 17, 2019: Karuna Therapeutics schedules webcast and conference call to announce results from its phase 2 clinical trial of KarXT for the treatment of Psychosis in patients with Schizophrenia
Nov 14, 2019: Anavex Life Sciences receives Rare Pediatric Disease Designation from FDA for ANAVEX2-73 (blarcamesine) for the treatment of Rett Syndrome
Nov 06, 2019: Anavex Life Sciences announces publication of foundational data for ANAVEX2-73 (blarcamesine) in Rett Syndrome
Oct 21, 2019: Cerevel Therapeutics initiates phase 1b clinical trial of CVL-231, a M4 selective positive allosteric modulator in development for the treatment of schizophrenia
Oct 10, 2019: Anavex initiates ANAVEX 2-73 study in Alzheimer disease
Oct 02, 2019: Anavex Life Sciences Issued New U.S. Patent for Composition of Matter Covering ANAVEX2-73 for the Treatment of Alzheimer’s Disease
Sep 27, 2019: Anavex Life Sciences presented at the 6th Annual European Rett Syndrome Conference preliminary clinical efficacy data from the U.S. Rett Syndrome Phase 2 ANAVEX2-73 Study
Sep 16, 2019: Anavex Life Sciences announces preliminary clinical efficacy data of its U.S. phase 2 clinical trial of ANAVEX 2-73 in patients with Rett Syndrome
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer

List of Tables
Number of Products under Development by Stage of Development, H1 2020
Number of Products under Development by Therapy Areas, H1 2020
Number of Products under Development by Indications, H1 2020
Number of Products under Development by Indications, H1 2020 (Contd..1), H1 2020
Number of Products under Development by Companies, H1 2020
Products under Development by Companies, H1 2020
Products under Development by Companies, H1 2020 (Contd..1), H1 2020
Products under Development by Companies, H1 2020 (Contd..2), H1 2020
Number of Products by Stage and Mechanism of Actions, H1 2020
Number of Products by Stage and Route of Administration, H1 2020
Number of Products by Stage and Molecule Type, H1 2020
Pipeline by Anavex Life Sciences Corp, H1 2020
Pipeline by AstraZeneca Plc, H1 2020
Pipeline by Cerevel Therapeutics LLC, H1 2020
Pipeline by Karuna Therapeutics Inc, H1 2020
Pipeline by NeuroHealing Pharmaceuticals Inc, H1 2020
Pipeline by NeuroSolis Inc, H1 2020
Pipeline by Presbyopia Therapies LLC, H1 2020
Pipeline by Sosei Heptares, H1 2020
Pipeline by Suven Life Sciences Ltd, H1 2020
Dormant Projects, H1 2020
Discontinued Products, H1 2020

【掲載企業】

Anavex Life Sciences Corp
AstraZeneca Plc
Cerevel Therapeutics LLC
Karuna Therapeutics Inc
NeuroHealing Pharmaceuticals Inc
NeuroSolis Inc
Presbyopia Therapies LLC
Sosei Heptares
Suven Life Sciences Ltd

【免責事項】
https://www.marketreport.jp/reports-disclaimer

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