低酸素誘導因子1アルファ治療薬市場:パイプラインレビュー(2019年下半期)

◆英語タイトル:Hypoxia Inducible Factor 1 Alpha - Pipeline Review, H2 2019
◆商品コード:GDATA20MY0362
◆発行会社(リサーチ会社):Global Markets Direct
◆発行日:2019年12月27日
◆ページ数:78
◆レポート言語:英語
◆レポート形式:PDF
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【レポートの概要】

Hypoxia Inducible Factor 1 Alpha – Pipeline Review, H2 2019
Summary

According to the recently published report ‘Hypoxia Inducible Factor 1 Alpha – Pipeline Review, H2 2019′; Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) pipeline Target constitutes close to 15 molecules. Out of which approximately 11 molecules are developed by companies and remaining by the universities/institutes.

Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) – Hypoxia-inducible factor 1-alpha is a subunit of a heterodimeric transcription factor encoded by the HIF1A gene. It plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. It activates the transcription of erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor and HILPDA under hypoxia condition.

The report ‘Hypoxia Inducible Factor 1 Alpha – Pipeline Review, H2 2019′ outlays comprehensive information on the Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.

It also reviews key players involved in Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Phase II, Phase I, Preclinical and Discovery stages are 1, 2, 6 and 2 respectively. Similarly, the universities portfolio in Preclinical stages comprises 4 molecules, respectively. Report covers products from therapy areas Oncology, Immunology, Cardiovascular, Central Nervous System, Dermatology, Metabolic Disorders and Ophthalmology which include indications Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia), Melanoma, Breast Cancer, Colorectal Cancer, Diabetic Foot Ulcers, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Gastric Cancer, Graft Versus Host Disease (GVHD), Hepatocellular Carcinoma, Ischemia, Kidney Cancer (Renal Cell Cancer), Lung Cancer, Metastatic Uveal Melanoma, Multiple Myeloma (Kahler Disease), Multiple Sclerosis, Peritoneal Cancer, Rectal Cancer, Small-Cell Lung Cancer, Systemic Sclerosis (Scleroderma), Transitional Cell Carcinoma (Urothelial Cell Carcinoma) and Wounds.

Scope

- The report provides a snapshot of the global therapeutic landscape for Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A)
- The report reviews Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) targeted therapeutics and enlists all their major and minor projects
- The report assesses Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) targeted therapeutics

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

【レポートの目次】

Table of Contents
List of Tables
List of Figures
Introduction
Global Markets Direct Report Coverage
Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) – Overview
Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) – Therapeutics Development
Products under Development by Stage of Development
Products under Development by Therapy Area
Products under Development by Indication
Products under Development by Companies
Products under Development by Universities/Institutes
Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) – Therapeutics Assessment
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) – Companies Involved in Therapeutics Development
Canton Biotechnologies Inc
Daiichi Sankyo Co Ltd
Emerald Health Sciences Inc
Ildong Pharmaceutical Co Ltd
Jiuzhitang Co Ltd
NewLink Genetics Corp
OliPass Corporation
OncoImmune Inc
OncoSpherix Inc
Phio Pharmaceuticals Corp
Vascular Biogenics Ltd
Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) – Drug Profiles
A-503451A – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Antisense Oligonucleotide to Inhibit HIF1A for Melanoma – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Antisense RNAi Oligonucleotides to Inhibit HIF-1 Alpha for Oncology and Retinal Disease – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
deferoxamine – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Echinomycin – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
EHP-101 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
FS-7 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Gene Therapy to Activate HIF-1 Alpha for Wound and Ulcers – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
HS-1793 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
IDF-11774 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
KCN-1 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
NLG-207 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
SR-16388 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
TR-764 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
VB-411 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) – Dormant Products
Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) – Discontinued Products
Hypoxia Inducible Factor 1 Alpha (ARNT Interacting Protein or Basic Helix Loop Helix PAS Protein MOP1 or Class E Basic Helix Loop Helix Protein 78 or Member Of PAS Protein 1 or PAS Domain Containing Protein 8 or HIF1A) – Product Development Milestones
Featured News & Press Releases
Aug 27, 2019: Emerald Health concludes Phase I trial of CBD-based therapeutic
Jul 02, 2019: Emerald Health Pharmaceuticals demonstrates repair of nerve damage related to multiple sclerosis
Jun 19, 2019: Emerald Health Pharmaceuticals to present Preclinical Data on EHP-101 at the 29th Annual Symposium of the International Cannabinoid Research Society
Apr 17, 2019: Emerald Health Pharmaceuticals receives U.S. Drug Enforcement Administration determination that the active ingredient in its lead product candidate is not a controlled substance
Apr 02, 2019: NewLink Genetics presents encouraging phase 2 results for NLG207 in ovarian cancer at AACR 2019
Mar 19, 2019: Emerald Health Pharmaceuticals cannabinoid-derived drug candidate, EHP-101, shows a unique mechanism of action in systemic sclerosis model, indicating key differences compared to ajulemic acid
Feb 27, 2019: NewLink Genetics announces clinical trial abstract presentation at AACR Annual Meeting
Feb 13, 2019: Emerald Health Pharmaceuticals and Lonza announce agreement for manufacturing of novel cannabinoid-derived drug candidate
Jan 23, 2019: Emerald Health Pharmaceuticals appoints Joachim P.H. Schupp, M.D., Dr. med. as Chief Medical Officer
Sep 28, 2018: EHP starts enrolment in EHP-101 Phase I trial for MS and scleroderma
Feb 15, 2018: Emerald Health Pharmaceuticals Granted European Orphan Designation for Systemic Scleroderma
Oct 20, 2017: Emerald Health Pharmaceuticals Granted FDA Orphan Drug Designation for Systemic Scleroderma
Oct 06, 2016: Cerulean Announces Clinical Data from CRLX101 Program at the 2016 European Society for Medical Oncology Annual Meeting
Aug 18, 2016: Cerulean Announces Reduction in Force
Aug 18, 2016: Cerulean Announces Results from Phase 2 Clinical Trial of CRLX101 and Avastin Combination in Relapsed Renal Cell Carcinoma
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer

List of Tables
Number of Products under Development by Stage of Development, H2 2019
Number of Products under Development by Therapy Areas, H2 2019
Number of Products under Development by Indications, H2 2019
Number of Products under Development by Indications, H2 2019 (Contd..1), H2 2019
Number of Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019 (Contd..1), H2 2019
Number of Products under Investigation by Universities/Institutes, H2 2019
Products under Investigation by Universities/Institutes, H2 2019
Number of Products by Stage and Mechanism of Actions, H2 2019
Number of Products by Stage and Route of Administration, H2 2019
Number of Products by Stage and Molecule Type, H2 2019
Pipeline by Canton Biotechnologies Inc, H2 2019
Pipeline by Daiichi Sankyo Co Ltd, H2 2019
Pipeline by Emerald Health Sciences Inc, H2 2019
Pipeline by Ildong Pharmaceutical Co Ltd, H2 2019
Pipeline by Jiuzhitang Co Ltd, H2 2019
Pipeline by NewLink Genetics Corp, H2 2019
Pipeline by OliPass Corporation, H2 2019
Pipeline by OncoImmune Inc, H2 2019
Pipeline by OncoSpherix Inc, H2 2019
Pipeline by Phio Pharmaceuticals Corp, H2 2019
Pipeline by Vascular Biogenics Ltd, H2 2019
Dormant Products, H2 2019
Dormant Products, H2 2019 (Contd..1), H2 2019
Dormant Products, H2 2019 (Contd..2), H2 2019
Discontinued Products, H2 2019

【掲載企業】

Canton Biotechnologies Inc
Daiichi Sankyo Co Ltd
Emerald Health Sciences Inc
Ildong Pharmaceutical Co Ltd
Jiuzhitang Co Ltd
NewLink Genetics Corp
OliPass Corporation
OncoImmune Inc
OncoSpherix Inc
Phio Pharmaceuticals Corp
Vascular Biogenics Ltd

【免責事項】
https://www.marketreport.jp/reports-disclaimer

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