血球貪食性リンパ組織球症治療薬の世界市場:インサイト・疫学・市場予測

◆英語タイトル:Hemophagocytic Lymphohistiocytosis - Market Insight, Epidemiology and Market Forecast - 2030
◆商品コード:DELV20JU054
◆発行会社(リサーチ会社):DelveInsight
◆発行日:2020年6月
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【レポートの概要】

DelveInsight’s ‘Hemophagocytic Lymphohistiocytosis Market Insights, Epidemiology, and Market Forecast – 2030’ report deliver an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Hemophagocytic Lymphohistiocytosis (HLH) in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

The Hemophagocytic Lymphohistiocytosis market report provides analysis regarding current treatment practices, an emerging drug-like Tadekinig Alfa, potential therapies, market share of the individual therapies, historical, current and forecasted Hemophagocytic Lymphohistiocytosis market size from 2017 to 2030 segmented by seven major markets.

The report also covers current Hemophagocytic Lymphohistiocytosis treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market.

Geography Covered
The United States
EU5 (Germany, France, Italy, Spain, and the United Kingdom)
Japan
Study Period: 2017–2030
Hemophagocytic Lymphohistiocytosis – Disease Understanding and Treatment Algorithm
Hemophagocytic Lymphohistiocytosis Overview

Hemophagocytic Lymphohistiocytosis (HLH) is a life-threatening disorder characterized by unbridled activation of cytotoxic T lymphocytes, natural killer (NK) cells, and macrophages resulting in hypercytokinemia and immune-mediated injury of multiple organ systems. HLH is a condition with different underlying causes.

The onset and severity of hemophagocytic lymphohistiocytosis can vary greatly from one person to another. Generally, affected individuals develop fevers, a rash, an abnormally large liver (hepatomegaly), and an abnormally large spleen (splenomegaly). However, these initial sign and symptoms are described as nonspecific. Affected individuals may also have anemia, thrombocytopenia, neurological symptoms including seizures, changes in mental status and irritability, paralysis (palsy) of certain cranial nerves, and problems coordinating voluntary movements (ataxia).

Hemophagocytic Lymphohistiocytosis Treatment
This chapter covers the details of conventional and current medical therapies available in the Hemophagocytic Lymphohistiocytosis market for the treatment of the condition. It also provides the country-wise Hemophagocytic Lymphohistiocytosis treatment guidelines across the United States, Europe and Japan.

DelveInsight’s Hemophagocytic Lymphohistiocytosis market report gives a thorough understanding of the disease by including details such as disease definition, symptoms, types, grading, pathophysiology, and diagnosis. It also provides Hemophagocytic Lymphohistiocytosis treatment algorithms and treatment guidelines in the US, Europe, and Japan.

Hemophagocytic Lymphohistiocytosis Epidemiology
The Hemophagocytic Lymphohistiocytosis epidemiology chapters provide insights about historical and current Hemophagocytic Lymphohistiocytosis patient pool and forecasted trend for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. Hemophagocytic Lymphohistiocytosis epidemiology is segmented by Incidence of Hemophagocytic Lymphohistiocytosis (Familial and secondary HLH), Familial HLH cases by Mutation Types and Secondary HLH cases by Etiologies. The report includes a thorough analysis of all segmentations.

Incidence of Hemophagocytic Lymphohistiocytosis can be divided into two subtypes: familial or primary HLH cases and secondary HLH cases. In the US, the cases of familial Hemophagocytic Lymphohistiocytosis were found to be 100 in 2017. Moreover, the cases of secondary HLH were reported to be 315 in the country.

According to DelveInsight’s, the total incident population of Hemophagocytic Lymphohistiocytosis in seven major markets was 4,435 in 2017. These cases are expected to increase with a significant CAGR during the study period (2017–2030).

Among all the seven major markets, Germany accounts for the highest number of Hemophagocytic Lymphohistiocytosis cases.

Hemophagocytic Lymphohistiocytosis Drug Chapters
Drug chapter segment of the Hemophagocytic Lymphohistiocytosis report encloses the detailed analysis of Hemophagocytic Lymphohistiocytosis pipeline drug. It also helps understand the Hemophagocytic Lymphohistiocytosis clinical trial details, expressive pharmacological action, agreements of included drug and the latest news and press releases.

The best treatment options for hemophagocytic lymphohistiocytosis (HLH) are determined by several factors, including the severity of symptoms, the age of onset, and the underlying cause of the condition. Treatment in adults has been based on the HLH-94 study, a large prospective pediatric study conducted by The Histiocyte Society in patients <16 years old with no history of immunosuppression or malignancy. AB2 Bio’s Tadekinig Alfa is the only therapy in the pipeline.

Hemophagocytic Lymphohistiocytosis Market Outlook
The Hemophagocytic Lymphohistiocytosis market size is expected to increase at a significant CAGR during the study period (2017–2030). Among all the seven major markets, France accounts for the largest Hemophagocytic Lymphohistiocytosis market size with USD 1.3 million in 2017, while Japan had the smallest market size of HLH with USD 0.2 million in 2017.

Hemophagocytic Lymphohistiocytosis Drugs Uptake
This section focusses on the rate of uptake of the potential drugs in the Hemophagocytic Lymphohistiocytosis market or expected to get launched in the market during the study period 2017–2030. The analysis covers Hemophagocytic Lymphohistiocytosis market uptake by drugs; patient uptake by therapies; and sale of each drug.

This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs, and allow the comparison of the drugs based on market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

The dynamics of HLH market is anticipated to experience a positive shift in the coming years owing to the expected launch of emerging therapy.

Hemophagocytic Lymphohistiocytosis Pipeline Development Activities
The report provides insights into different therapeutic candidates in Phase II, and Phase III stage. It also analyses Hemophagocytic Lymphohistiocytosis key players involved in developing targeted therapeutics.

Pipeline Development Activities

The report covers the detailed information of Hemophagocytic Lymphohistiocytosis collaborations, acquisition and merger, licensing, patent details and other information for Hemophagocytic Lymphohistiocytosis emerging therapies.

Reimbursement Scenario in Hemophagocytic Lymphohistiocytosis
Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In a report, we consider reimbursement to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.

KOL Views
To keep up with current market trends, we take KOLs and SME’s opinion working in Hemophagocytic Lymphohistiocytosis domain through primary research to fill the data gaps and validate our secondary research. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the market and the unmet needs.

Competitive Intelligence Analysis
We perform Competitive and Market Intelligence analysis of the Hemophagocytic Lymphohistiocytosis Market by using various Competitive Intelligence tools that include – SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies etc. The inclusion of the analysis entirely depends upon the data availability.

Report Highlights
In the coming years, Hemophagocytic Lymphohistiocytosis market scenario is not expected to alter much across the 7MM due to lack of approved treatment options and a static pipeline. Lack of adequate research and development activities funded by major pharma players is also making an impact on the overall landscape.
Our in-depth analysis of the pipeline assets across different stages of development (Phase II), different emerging trends and comparative analysis of pipeline products with detailed clinical profiles, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities.
Hemophagocytic Lymphohistiocytosis Report Insights
Patient Population
Therapeutic Approaches
Hemophagocytic Lymphohistiocytosis Pipeline Analysis
Hemophagocytic Lymphohistiocytosis Market Size and Trends
Market Opportunities
Impact of upcoming Therapies
Hemophagocytic Lymphohistiocytosis Report Key Strengths
11 years Forecast
7MM Coverage
Hemophagocytic Lymphohistiocytosis Epidemiology Segmentation
Key Cross Competition
Highly Analyzed Market
Drugs Uptake
Hemophagocytic Lymphohistiocytosis Report Assessment
Pipeline Product Profiles
Key Products and Key Players
Market Drivers and Barriers
Key Questions
Market Insights:

What was the Hemophagocytic Lymphohistiocytosis market share (%) distribution in 2017 and how it would look like in 2030?
What would be the Hemophagocytic Lymphohistiocytosis total market size as well as market size by therapies across the 7MM during the forecast period (2017–2030)?
What are the key findings pertaining to the market across 7MM and which country will have the largest Hemophagocytic Lymphohistiocytosis market size during the forecast period (2017–2030)?
At what CAGR, the Hemophagocytic Lymphohistiocytosis market is expected to grow in 7MM during the forecast period (2017–2030)?
What would be the Hemophagocytic Lymphohistiocytosis market outlook across the 7MM during the forecast period (2017–2030)?
What would be the Hemophagocytic Lymphohistiocytosis market growth till 2030, and what will be the resultant market Size in the year 2030?
How would the market drivers, barriers and future opportunities affect the market dynamics and subsequent analysis of the associated trends?
Epidemiology Insights:

What is the disease risk, burden and unmet needs of Hemophagocytic Lymphohistiocytosis?
What is the historical Hemophagocytic Lymphohistiocytosis patient pool in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
What would be the forecasted patient pool of Hemophagocytic Lymphohistiocytosis in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
What will be the growth opportunities in the 7MM with respect to the patient population pertaining to Hemophagocytic Lymphohistiocytosis?
Out of all 7MM countries, which country would have the highest incidence population of Hemophagocytic Lymphohistiocytosis during the forecast period (2017–2030)?
At what CAGR the population is expected to grow in 7MM during the forecast period (2017–2030)?
Current Treatment Scenario, Marketed Drugs, and Emerging Therapies:
What are the current options for the Hemophagocytic Lymphohistiocytosis treatment, along with the approved therapy?
What are the current treatment guidelines for the treatment of Hemophagocytic Lymphohistiocytosis in the USA, Europe, and Japan?
What are the Hemophagocytic Lymphohistiocytosis marketed drugs and their MOA, regulatory milestones, product development activities, advantages, disadvantages, safety and efficacy, etc.?
How many companies are developing therapies for the treatment of Hemophagocytic Lymphohistiocytosis?
How many therapies are developed by each company for Hemophagocytic Lymphohistiocytosis treatment?
How many are emerging therapies in mid-stage, and late stage of development for Hemophagocytic Lymphohistiocytosis treatment?
What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Hemophagocytic Lymphohistiocytosis therapies?
What are the recent novel therapies, targets, mechanisms of action and technologies developed to overcome the limitation of existing therapies?
What are the clinical studies going on for Hemophagocytic Lymphohistiocytosis and their status?
What are the key designations that have been granted for the emerging therapies for Hemophagocytic Lymphohistiocytosis?
What are the global historical and forecasted market of Hemophagocytic Lymphohistiocytosis?
Reasons to buy
The report will help in developing business strategies by understanding trends shaping and driving the Hemophagocytic Lymphohistiocytosis market
To understand the future market competition in the Hemophagocytic Lymphohistiocytosis market and Insightful review of the key market drivers and barriers
Organize sales and marketing efforts by identifying the best opportunities for Hemophagocytic Lymphohistiocytosis in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
Organize sales and marketing efforts by identifying the best opportunities for Hemophagocytic Lymphohistiocytosis market
To understand the future market competition in the Hemophagocytic Lymphohistiocytosis market

Which geography accounted for the largest Hemophagocytic Lymphohistiocytosis market size?

France accounted for the largest Hemophagocytic Lymphohistiocytosis market size.

What is forecasted Hemophagocytic Lymphohistiocytosis market size in 2030?

DelveInsight estimates an increase in HLH Market Size during the study period, 2017–2030

What are the present Hemophagocytic Lymphohistiocytosis market drivers?

Increasing prevalence of risk factors and research opportunities.

What are the Hemophagocytic Lymphohistiocytosis market barriers?

Toxicity of therapies, lack of specialized therapies, and lack of alternative treatments.

How many companies are developing drugs for Hemophagocytic Lymphohistiocytosis?

Currently, only one key pharma player is developing a drug for Hemophagocytic Lymphohistiocytosis.

Which are the leading companies in Hemophagocytic Lymphohistiocytosis market?

Key Player – AB2 Bio

How is epidemiology segmented for Hemophagocytic Lymphohistiocytosis?

Incidence of Hemophagocytic Lymphohistiocytosis, Familial HLH cases by Mutation Types and Secondary HLH cases by Etiologies.

【レポートの目次】

1 Key Insights

2 Executive Summary of Hemophagocytic Lymphohistiocytosis

3 SWOT Analysis for HLH

4 Hemophagocytic Lymphohistiocytosis Market Overview at a Glance

4.1 Market Share (%) Distribution of Hemophagocytic Lymphohistiocytosis in 2017

4.2 Market Share (%) Distribution of Hemophagocytic Lymphohistiocytosis in 2030

5 Disease Background and Overview

5.1 Introduction

5.2 History

5.3 Classification

5.4 Sub-types

5.5 Causes

5.6 Symptoms

5.7 Clinical Presentation

5.8 Pathophysiology

5.9 Diagnosis

6 Epidemiology and Patient Population

6.1 Key Findings

6.2 Assumptions and Rationale – 7MM

6.3 7MM Total Incident Patient Population of Hemophagocytic Lymphohistiocytosis

7 Country Wise-Epidemiology of Hemophagocytic Lymphohistiocytosis

7.1 The United States

7.1.1 Total Incident Cases of Hemophagocytic Lymphohistiocytosis in the United States

7.1.2 Familial Hemophagocytic Lymphohistiocytosis cases by Mutation Types in the United States

7.1.3 Secondary HLH Cases by Etiologies in the United States

7.2 EU5

7.2.1 Germany

7.2.2 France

7.2.3 Italy

7.2.4 Spain

7.2.5 The United Kingdom

7.2.6 Japan

8 Treatment

8.1 Guidelines

8.1.1 HLH-2004: Diagnostic and Therapeutic Guidelines for Hemophagocytic Lymphohistiocytosis

8.1.2 Management of Hemophagocytic Lymphohistiocytosis

9 Unmet Needs

10 Organizations contributing toward Hemophagocytic Lymphohistiocytosis

11 KOL’s Views: Hemophagocytic Lymphohistiocytosis

12 Case Studies

12.1 Fever of Unknown Origin

12.2 A Challenging Diagnosis

13 Marketed Drugs

13.1 Gamifant (Emapalumab): Swedish Orphan Biovitrum

13.1.1 Product Description

13.1.2 Product Developmental Activity

13.1.3 Clinical Development

13.1.4 Safety and Efficacy

14 Emerging Therapies

14.1 Tadekinig alfa (IL-18BP): AB2 Bio

14.1.1 Drug Description

14.1.2 Other Developmental Activities

14.1.3 Clinical Development

15 Hemophagocytic Lymphohistiocytosis: Seven Major Market Analysis

15.1 Key Findings

15.1 Hemophagocytic Lymphohistiocytosis: Market Outlook

15.2 Market Size of Hemophagocytic Lymphohistiocytosis in 7MM

16 Market Outlook by Country

16.1 United States Market Size

16.1.1 Total Market Size of Hemophagocytic Lymphohistiocytosis

16.1.2 Total Market Size of Familial HLH

16.1.3 Total Market Size of Secondary HLH

16.2 EU-5 Countries: Market

16.2.1 Germany

16.2.2 France

16.2.3 Italy

16.2.4 Spain

16.2.5 United Kingdom

16.3 Japan: Market

16.3.1 Total Market Size of Hemophagocytic Lymphohistiocytosis

16.3.2 Total Market Size of Familial HLH

16.3.3 Total Market Size of Secondary HLH

17 Market Drivers

18 Market Barriers

19 Appendix

19.1 Report Methodology

19.2 Bibliography

20 DelveInsight Capabilities

21 Disclaimer

22 About DelveInsight

Table 1: Summary of Hemophagocytic Lymphohistiocytosis Market, Epidemiology, and Key Events (2017–2030)

Table 2: Histiocytoses of the H group: classification of HLH

Table 3: List of abnormalities associated with HLH

Table 4: Clinical Manifestations associated with HLH in Children and Adults

Table 5: Laboratory Presentations associated with HLH in Children and Adults

Table 6: HLH-2004 Diagnostic Criteria

Table 7: Historical Review of Nomenclature and Diagnostic Criteria in HLH

Table 8: The HScore

Table 9: Genetic Testing in HLH

Table 10: Incident Patient Population of Hemophagocytic Lymphohistiocytosis in 7MM (2017–2030)

Table 11: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in the United States (2017–2030)

Table 12: Hemophagocytic Lymphohistiocytosis cases by Mutation Types in the United States (2017–2030)

Table 13: Secondary HLH Cases by Etiologies in the United States (2017–2030)

Table 14: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in Germany (2017–2030)

Table 15: Familial Hemophagocytic Lymphohistiocytosis cases by Mutation Types in Germany (2017–2030)

Table 16: Secondary HLH Cases by Etiologies in Germany (2017–2030)

Table 17: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in France (2017–2030)

Table 18: Familial Hemophagocytic Lymphohistiocytosis cases by Mutation Types in France (2017–2030)

Table 19: Secondary HLH Cases by Etiologies in France (2017–2030)

Table 20: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in Italy (2017–2030)

Table 21: Familial Hemophagocytic Lymphohistiocytosis cases by Mutation Types in Italy (2017–2030)

Table 22: Secondary HLH Cases by Etiologies in Italy (2017–2030)

Table 23: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in Spain (2017–2030)

Table 24: Familial Hemophagocytic Lymphohistiocytosis cases by Mutation Types in Spain (2017–2030)

Table 25: Secondary HLH Cases by Etiologies in Spain (2017–2030)

Table 26: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in the United Kingdom (2017–2030)

Table 27: Familial Hemophagocytic Lymphohistiocytosis cases by Mutation Types in the UK (2017–2030)

Table 28: Secondary HLH Cases by Etiologies in the UK (2017–2030)

Table 29: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in Japan (2017–2030)

Table 30: Familial Hemophagocytic Lymphohistiocytosis cases by Mutation Types in Japan (2017–2030)

Table 31: Secondary HLH Cases by Etiologies in Japan (2017–2030)

Table 32: Organizations contributing toward HLH

Table 33: Gamifant, Clinical Trial Description, 2020

Table 34: Tadekinig alfa, Clinical Trial Description, 2020

Table 35: 7 Major Market Size of Hemophagocytic Lymphohistiocytosis in USD Million (2017–2030)

Table 36: United States Market Size of Hemophagocytic Lymphohistiocytosis in USD Million (2017–2030)

Table 37: United States Market Size of Familial HLH in USD Million (2017–2030)

Table 38: United States Market Size of Secondary HLH in USD Million (2017–2030)

Table 39: Germany Market Size of Hemophagocytic Lymphohistiocytosis in USD Million (2017–2030)

Table 40: Germany Market Size of Familial HLH in USD Million (2017–2030)

Table 41: Germany Market Size of Secondary HLH in USD Million (2017–2030)

Table 42: France Market Size of Hemophagocytic Lymphohistiocytosis in USD Million (2017–2030)

Table 43: France Market Size of Familial HLH in USD Million (2017–2030)

Table 44: France Market Size of Secondary HLH in USD Million (2017–2030)

Table 45: Italy Market Size of Hemophagocytic Lymphohistiocytosis in USD Million (2017–2030)

Table 46: Italy Market Size of Familial HLH in USD Million (2017–2030)

Table 47: Italy Market Size of Secondary HLH in USD Million (2017–2030)

Table 48: Spain Market Size of Hemophagocytic Lymphohistiocytosis in USD Million (2017–2030)

Table 49: Spain Market Size of Familial HLH in USD Million (2017–2030)

Table 50: Spain Market Size of Secondary HLH in USD Million (2017–2030)

Table 51: United Kingdom Market Size of Hemophagocytic Lymphohistiocytosis in USD Million (2017–2030)

Table 52: United Kingdom Market Size of Familial HLH in USD Million (2017–2030)

Table 53: United Kingdom Market Size of Secondary HLH in USD Million (2017–2030)

Table 54: Japan Market Size of Hemophagocytic Lymphohistiocytosis in USD Million (2017–2030)

Table 55: Japan Market Size of Familial HLH in USD Million (2017–2030)

Table 56: Japan Market Size of Secondary HLH in USD Million (2017–2030)



List of Figures

Figure 1: SWOT Analysis

Figure 2: Pathogenesis of HLH

Figure 3: Normal Cytotoxic Function

Figure 4: Pathophysiology of Primary HLH

Figure 5: Pathophysiology of HLH due to Inborn Errors of Immunity

Figure 6: Mechanisms Through Which Viruses Contribute to HLH

Figure 7: Pathogenic Mechanisms contributing to HLH

Figure 8: Mechanisms that contribute to increased predisposition to MAS

Figure 9: A General Approach Towards the Diagnosis of HLH

Figure 10: Incident Patient Population of Hemophagocytic Lymphohistiocytosis in 7MM (2017–2030)

Figure 11: Total Incident Cases of HLH in the United States (2017–2030)

Figure 12: Familial HLH cases by Mutation Types in the United States (2017–2030)

Figure 13: Secondary HLH Cases by Etiologies in the United States (2017–2030)

Figure 14: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in Germany (2017–2030)

Figure 15: Familial HLH cases by Mutation Types in Germany (2017–2030)

Figure 16: Secondary HLH Cases by Etiologies in Germany (2017–2030)

Figure 17: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in France (2017–2030)

Figure 18: Familial HLH cases by Mutation Types in France (2017–2030)

Figure 19: Secondary HLH Cases by Etiologies in France (2017–2030)

Figure 20: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in Italy (2017–2030)

Figure 21: Familial Hemophagocytic Lymphohistiocytosis cases by Mutation Types in Italy (2017–2030)

Figure 22: Secondary HLH Cases by Etiologies in Italy (2017–2030)

Figure 23: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in Spain (2017–2030)

Figure 24: Familial HLH cases by Mutation Types in Spain (2017–2030)

Figure 25: Secondary HLH Cases by Etiologies in Spain (2017–2030)

Figure 26: Total Incident Cases of HLH in the United Kingdom (2017–2030)

Figure 27: Familial HLH cases by Mutation Types in the UK (2017–2030)

Figure 28: Secondary HLH Cases by Etiologies in the UK (2017–2030)

Figure 29: Total Incident Cases of Hemophagocytic Lymphohistiocytosis in Japan (2017–2030)

Figure 30: Familial HLH cases by Mutation Types in Japan (2017–2030)

Figure 31: Secondary HLH Cases by Etiologies in Japan (2017–2030)

Figure 32: Treatment Algorithm of HLH in Adults

Figure 33: Treatment Algorithm of HLH in Adults

Figure 34: Treatment Algorithm of HLH in Adults including MAS-HLH

Figure 35: Algorithm for treating HLH among Children

Figure 36: HLH-2004: Schematic Treatment Overview

Figure 37: Unmet Needs of Hemophagocytic Lymphohistiocytosis

Figure 38: 7 Major Market Size of HLH (fHLH and sHLH) in USD Million (2017–2030)

Figure 39: Market Size of HLH in the United States, USD Million (2017–2030)

Figure 40: Market Size of Familial HLH in the United States, USD Million (2017–2030)

Figure 41: Market Size of Secondary HLH in the United States, USD Million (2017–2030)

Figure 42: Market Size of HLH in Germany, USD Million (2017–2030)

Figure 43: Market Size of Familial HLH in Germany, USD Million (2017–2030)

Figure 44: Market Size of Secondary HLH in Germany, USD Million (2017–2030)

Figure 45: Market Size of HLH in France, USD Million (2017–2030)

Figure 46: Market Size of Familial HLH in France, USD Million (2017–2030)

Figure 47: Market Size of Secondary HLH in France, USD Million (2017–2030)

Figure 48: Market Size of HLH in Italy, USD Million (2017–2030)

Figure 49: Market Size of Familial HLH in Italy, USD Million (2017–2030)

Figure 50: Market Size of Secondary HLH in Italy, USD Million (2017–2030)

Figure 51: Market Size of HLH in Spain, USD Million (2017–2030)

Figure 52: Market Size of Familial HLH in Spain, USD Million (2017–2030)

Figure 53: Market Size of Secondary HLH in Spain, USD Million (2017–2030)

Figure 54: Market Size of HLH in the United Kingdom, USD Million (2017–2030)

Figure 55: Market Size of Familial HLH in the United Kingdom, USD Million (2017–2030)

Figure 56: Market Size of Secondary HLH in the United Kingdom, USD Million (2017–2030)

Figure 57: Market Size of HLH in Japan, USD Million (2017–2030)

Figure 58: Market Size of Familial HLH in Japan, USD Million (2017–2030)

Figure 59: Market Size of Secondary HLH in Japan, USD Million (2017–2030)

Figure 60: Market Drivers

Figure 61: Market Barriers

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