Critical Limb Ischemia:治療薬開発パイプライン動向(2014年上半期、グローバル製薬市場)

◆英語タイトル:Critical Limb Ischemia - Pipeline Review, H1 2014
◆商品コード:GMDHC5083IDB
◆発行会社(リサーチ会社):Global Markets Direct
◆発行日:2014年6月30日
◆ページ数:124
◆レポート言語:英語
◆レポート形式:PDF
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◆調査対象地域:グローバル
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【レポートの概要】

Critical Limb Ischemia – Pipeline Review, H1 2014

Summary

Global Markets Direct’s, ‘Critical Limb Ischemia – Pipeline Review, H1 2014’, provides an overview of the Critical Limb Ischemia’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Critical Limb Ischemia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Critical Limb Ischemia and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Critical Limb Ischemia
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in the therapeutics development for Critical Limb Ischemia and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects
- A review of the Critical Limb Ischemia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Critical Limb Ischemia pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Critical Limb Ischemia
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Critical Limb Ischemia pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

【レポートの目次】

Table of Contents
Table of Contents 2
List of Tables 6
List of Figures 7
Introduction 8
Global Markets Direct Report Coverage 8
Critical Limb Ischemia Overview 9
Therapeutics Development 10
Pipeline Products for Critical Limb Ischemia – Overview 10
Pipeline Products for Critical Limb Ischemia – Comparative Analysis 11
Critical Limb Ischemia – Therapeutics under Development by Companies 12
Critical Limb Ischemia – Therapeutics under Investigation by Universities/Institutes 15
Critical Limb Ischemia – Pipeline Products Glance 16
Late Stage Products 16
Clinical Stage Products 17
Early Stage Products 18
Critical Limb Ischemia – Products under Development by Companies 19
Critical Limb Ischemia – Products under Investigation by Universities/Institutes 20
Critical Limb Ischemia – Companies Involved in Therapeutics Development 21
Aastrom Biosciences, Inc. 21
Athersys, Inc. 22
Cytomedix, Inc. 23
ReNeuron Group plc 24
AnGes MG, Inc. 25
Pluristem Therapeutics Inc. 26
Juventas Therapeutics, Inc. 27
Intrexon Corporation 28
ViroMed Co., Ltd. 29
K-Stemcell Co., Ltd. 30
Pharmicell Co., Ltd. 31
Stempeutics Research Private Limited 32
Targazyme, Inc. 33
Multi Gene Vascular Systems Ltd 34
Apceth GmbH & Co. KG 35
Kasiak Research Pvt. Ltd. 36
Hemostemix Ltd 37
Critical Limb Ischemia – Therapeutics Assessment 38
Assessment by Monotherapy Products 38
Assessment by Target 39
Assessment by Mechanism of Action 41
Assessment by Route of Administration 43
Assessment by Molecule Type 45
Drug Profiles 47
ixmyelocel-T – Drug Profile 47
Product Description 47
Mechanism of Action 47
R&D Progress 47
beperminogene perplasmid – Drug Profile 50
Product Description 50
Mechanism of Action 50
R&D Progress 50
VM-202 – Drug Profile 53
Product Description 53
Mechanism of Action 53
R&D Progress 53
JVS-100 – Drug Profile 55
Product Description 55
Mechanism of Action 55
R&D Progress 55
Stempeucel-CLI – Drug Profile 57
Product Description 57
Mechanism of Action 57
R&D Progress 57
ACP-01 – Drug Profile 58
Product Description 58
Mechanism of Action 58
R&D Progress 58
ASCT-01 – Drug Profile 60
Product Description 60
Mechanism of Action 60
R&D Progress 60
ALD-301 – Drug Profile 61
Product Description 61
Mechanism of Action 61
R&D Progress 61
MultiGeneAngio – Drug Profile 63
Product Description 63
Mechanism of Action 63
R&D Progress 63
Alecmestencel-T – Drug Profile 64
Product Description 64
Mechanism of Action 64
R&D Progress 64
ERC-124 – Drug Profile 65
Product Description 65
Mechanism of Action 65
R&D Progress 65
Autologous Adipose Tissue Derived Mesenchymal Stem Cell – Drug Profile 66
Product Description 66
Mechanism of Action 66
R&D Progress 66
Refacell-CLI – Drug Profile 68
Product Description 68
Mechanism of Action 68
R&D Progress 68
Stem Cell Therapy for Cardiovascular Diseases – Drug Profile 69
Product Description 69
Mechanism of Action 69
R&D Progress 69
ReN-009 – Drug Profile 71
Product Description 71
Mechanism of Action 71
R&D Progress 71
Autologous Bone Marrow Mononuclear Cells – Drug Profile 72
Product Description 72
Mechanism of Action 72
R&D Progress 72
MultiStem – Drug Profile 73
Product Description 73
Mechanism of Action 73
R&D Progress 73
Stromal Cell Therapy For Critical Limb Ischemia – Drug Profile 76
Product Description 76
Mechanism of Action 76
R&D Progress 76
ASC-101 – Drug Profile 77
Product Description 77
Mechanism of Action 77
R&D Progress 77
Stem Cell Therapy for Critical Limb Ischemia – Drug Profile 78
Product Description 78
Mechanism of Action 78
R&D Progress 78
Cell Therapy for Critical Limb Ischemia – Drug Profile 79
Product Description 79
Mechanism of Action 79
R&D Progress 79
Recombinant Protein for Critical Limb Ischemia and Wounds – Drug Profile 80
Product Description 80
Mechanism of Action 80
R&D Progress 80
Stem Cells Therapy for Critical Limb Ischemia – Drug Profile 81
Product Description 81
Mechanism of Action 81
R&D Progress 81
Cellgram for Severe Lower Limb Ischemia – Drug Profile 82
Product Description 82
Mechanism of Action 82
R&D Progress 82
Stem Cell Therapy for Critical Limb Ischemia – Drug Profile 83
Product Description 83
Mechanism of Action 83
R&D Progress 83
Critical Limb Ischemia – Recent Pipeline Updates 84
Critical Limb Ischemia – Dormant Projects 114
Critical Limb Ischemia – Discontinued Products 115
Critical Limb Ischemia – Product Development Milestones 116
Featured News & Press Releases 116
Mar 27, 2014: ReNeuron receives UK regulatory approvals for Phase II clinical trial in stroke and Phase I clinical trial in critical limb ischaemia 116
Mar 26, 2014: Mast Therapeutics Initiates Phase 2 Study Of MST-188 In Patients With Acute Limb Ischemia 117
Dec 19, 2013: Aastrom Biosciences Granted Composition-of-Matter Patent for Ixmyelocel-T in Australia 118
Dec 17, 2013: Bioheart Announces Clinical Study for Dry Macular Degeneration 118
Sep 25, 2013: Medistem to Present at Aegis Capital 2013 Healthcare Conference 118
Jul 31, 2013: Medistem Presents Its ERC-124 Stem Cell Product at CRYO 2013 119
Jul 29, 2013: Medistem Enters Collaboration With Boston Academic Teaching Hospital to Expand Preclinical Data in Type 1 Diabetes 119
Jul 23, 2013: Mast Therapeutics Reports Results From Clinical QT Study Of MST-188 120
Apr 10, 2013: Athersys Announces Publication Of Study Results Demonstrating Relevance Of MultiStem For Autoimmune Disease, Transplantation And Vascular Disease 120
Mar 27, 2013: Aastrom Biosciences Announces Strategic Change In R&D Programs To Focus On Dilated Cardiomyopathy And Other Rare Disease Indications 121
Appendix 123
Methodology 123
Coverage 123
Secondary Research 123
Primary Research 123
Expert Panel Validation 123
Contact Us 124
Disclaimer 124

List of Tables
Number of Products under Development for Critical Limb Ischemia, H1 2014 10
Number of Products under Development for Critical Limb Ischemia - Comparative Analysis, H1 2014 11
Number of Products under Development by Companies, H1 2014 13
Number of Products under Development by Companies, H1 2014 (Contd..1) 14
Number of Products under Investigation by Universities/Institutes, H1 2014 15
Comparative Analysis by Late Stage Development, H1 2014 16
Comparative Analysis by Clinical Stage Development, H1 2014 17
Comparative Analysis by Early Stage Development, H1 2014 18
Products under Development by Companies, H1 2014 19
Products under Investigation by Universities/Institutes, H1 2014 20
Critical Limb Ischemia - Pipeline by Aastrom Biosciences, Inc., H1 2014 21
Critical Limb Ischemia - Pipeline by Athersys, Inc., H1 2014 22
Critical Limb Ischemia - Pipeline by Cytomedix, Inc, H1 2014 23
Critical Limb Ischemia - Pipeline by ReNeuron Group plc, H1 2014 24
Critical Limb Ischemia - Pipeline by AnGes MG, Inc., H1 2014 25
Critical Limb Ischemia - Pipeline by Pluristem Therapeutics Inc., H1 2014 26
Critical Limb Ischemia - Pipeline by Juventas Therapeutics, Inc., H1 2014 27
Critical Limb Ischemia - Pipeline by Intrexon Corporation., H1 2014 28
Critical Limb Ischemia - Pipeline by ViroMed Co., Ltd., H1 2014 29
Critical Limb Ischemia - Pipeline by K-Stemcell Co., Ltd., H1 2014 30
Critical Limb Ischemia - Pipeline by Pharmicell Co., Ltd., H1 2014 31
Critical Limb Ischemia - Pipeline by Stempeutics Research Private Limited, H1 2014 32
Critical Limb Ischemia - Pipeline by Targazyme, Inc., H1 2014 33
Critical Limb Ischemia - Pipeline by Multi Gene Vascular Systems Ltd., H1 2014 34
Critical Limb Ischemia - Pipeline by Apceth GmbH & Co. KG., H1 2014 35
Critical Limb Ischemia - Pipeline by Kasiak Research Pvt. Ltd., H1 2014 36
Critical Limb Ischemia - Pipeline by Hemostemix Ltd, H1 2014 37
Assessment by Monotherapy Products, H1 2014 38
Number of Products by Stage and Target, H1 2014 40
Number of Products by Stage and Mechanism of Action, H1 2014 42
Number of Products by Stage and Route of Administration, H1 2014 44
Number of Products by Stage and Molecule Type, H1 2014 46
Critical Limb Ischemia Therapeutics - Recent Pipeline Updates, H1 2014 84
Critical Limb Ischemia - Dormant Projects, H1 2014 114
Critical Limb Ischemia - Discontinued Products, H1 2014 115

List of Figures
Number of Products under Development for Critical Limb Ischemia, H1 2014 10
Number of Products under Development for Critical Limb Ischemia - Comparative Analysis, H1 2014 11
Number of Products under Development by Companies, H1 2014 12
Number of Products under Investigation by Universities/Institutes, H1 2014 15
Comparative Analysis by Clinical Stage Development, H1 2014 17
Comparative Analysis by Early Stage Products, H1 2014 18
Assessment by Monotherapy Products, H1 2014 38
Number of Products by Top 10 Target, H1 2014 39
Number of Products by Stage and Top 10 Target, H1 2014 40
Number of Products by Top 10 Mechanism of Action, H1 2014 41
Number of Products by Stage and Top 10 Mechanism of Action, H1 2014 42
Number of Products by Top 10 Route of Administration, H1 2014 43
Number of Products by Stage and Top 10 Route of Administration, H1 2014 44
Number of Products by Top 10 Molecule Type, H1 2014 45
Number of Products by Stage and Top 10 Molecule Type, H1 2014 46

【掲載企業】

Aastrom Biosciences, Inc.
Athersys, Inc.
Cytomedix, Inc.
ReNeuron Group plc
AnGes MG, Inc.
Pluristem Therapeutics Inc.
Juventas Therapeutics, Inc.
Intrexon Corporation
ViroMed Co., Ltd.
K-Stemcell Co., Ltd.
Pharmicell Co., Ltd.
Stempeutics Research Private Limited
Targazyme, Inc.
Multi Gene Vascular Systems Ltd
Apceth GmbH & Co. KG
Kasiak Research Pvt. Ltd.
Hemostemix Ltd

【免責事項】
https://www.marketreport.jp/reports-disclaimer

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