線維芽細胞成長因子受容体4治療薬市場:パイプラインレビュー(2019年下半期)

◆英語タイトル:Fibroblast Growth Factor Receptor 4 - Pipeline Review, H2 2019
◆商品コード:GDATA20MY0440
◆発行会社(リサーチ会社):Global Markets Direct
◆発行日:2019年12月27日
◆ページ数:145
◆レポート言語:英語
◆レポート形式:PDF
◆納品方法:Eメール
◆調査対象地域:グローバル
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【レポートの概要】

Fibroblast Growth Factor Receptor 4 – Pipeline Review, H2 2019
Summary

According to the recently published report ‘Fibroblast Growth Factor Receptor 4 – Pipeline Review, H2 2019′; Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) pipeline Target constitutes close to 23 molecules. Out of which approximately 21 molecules are developed by companies and remaining by the universities/institutes.

Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) – Fibroblast growth factor receptor 4 is a protein encoded by the FGFR4 gene. It plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. It is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. It phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades.

The report ‘Fibroblast Growth Factor Receptor 4 – Pipeline Review, H2 2019′ outlays comprehensive information on the Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.

It also reviews key players involved in Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical and Discovery stages are 1, 5, 4, 6, 1, 1 and 3 respectively. Similarly, the universities portfolio in Phase I and Preclinical stages comprises 1 and 1 molecules, respectively.

Report covers products from therapy areas Oncology, Gastrointestinal, Metabolic Disorders, Central Nervous System and Musculoskeletal Disorders which include indications Hepatocellular Carcinoma, Bile Duct Cancer (Cholangiocarcinoma), Solid Tumor, Breast Cancer, Gastric Cancer, Glioblastoma Multiforme (GBM), Lung Adenocarcinoma, Metastatic Transitional (Urothelial) Tract Cancer, Ovarian Cancer, Transitional Cell Carcinoma (Urothelial Cell Carcinoma), Type 2 Diabetes, Bladder Cancer, Esophageal Cancer, Head And Neck Cancer Squamous Cell Carcinoma, Liver Cancer, Non Muscle Invasive Bladder Cancer (NMIBC) (Superficial Bladder Cancer), Non-Alcoholic Steatohepatitis (NASH), Obesity, Prostate Cancer, Squamous Non-Small Cell Lung Cancer, Thyroid Cancer, Transitional Cell Cancer (Urothelial Cell Cancer), Achondroplasia, Adenoid Cystic Carcinoma (ACC), Adrenocortical Carcinoma (Adrenal Cortex Cancer), Anaplastic Thyroid Cancer, Colorectal Cancer, Constipation, Endometrial Cancer, Epithelial Ovarian Cancer, Ewing Sarcoma, Fallopian Tube Cancer, Gallbladder Cancer, Gastrointestinal Tract Cancer, Head And Neck Cancer, High-Grade Glioma, Lymphoma, Melanoma, Metastatic Bile Duct Cancer, Metastatic Biliary Tract Cancer, Metastatic Melanoma, Metastatic Renal Cell Carcinoma, Nasopharyngeal Cancer, Non-Small Cell Lung Cancer, Oral Mucositis, Osteosarcoma, Peritoneal Cancer, Primary Biliary Cholangitis (Primary Biliary Cirrhosis), Primary Sclerosing Cholangitis, Primitive Neuroectodermal Tumor (PNET), Recurrent Head And Neck Cancer Squamous Cell Carcinoma, Refractory Acute Myeloid Leukemia, Refractory Multiple Myeloma, Relapsed Acute Myeloid Leukemia, Relapsed Multiple Myeloma, Renal Cell Carcinoma, Rhabdomyosarcoma, Small-Cell Lung Cancer, Spinal Cord Injury, Squamous Cell Carcinoma, Thymic Carcinoma and Triple-Negative Breast Cancer (TNBC).

Scope

- The report provides a snapshot of the global therapeutic landscape for Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1)
- The report reviews Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) targeted therapeutics and enlists all their major and minor projects
- The report assesses Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) targeted therapeutics

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

【レポートの目次】

Table of Contents
List of Tables
List of Figures
Introduction
Global Markets Direct Report Coverage
Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) – Overview
Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) – Therapeutics Development
Products under Development by Stage of Development
Products under Development by Therapy Area
Products under Development by Indication
Products under Development by Companies
Products under Development by Universities/Institutes
Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) – Therapeutics Assessment
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) – Companies Involved in Therapeutics Development
Abbisko Therapeutics Co Ltd
Akero Therapeutics Inc
ArQule Inc
Bayer AG
Blueprint Medicines Corp
Eddingpharm Inc
Eisai Co Ltd
Eli Lilly and Co
EUSOL Biotech Co Ltd
Everest Medicines Ltd
Genosco Inc
H3 Biomedicine Inc
ImmunoForge Co Ltd
Incyte Corp
InnoCare Pharma Ltd
Johnson & Johnson
NGM Biopharmaceuticals Inc
Principia Biopharma Inc
QED Therapeutics Inc
Vichem Chemie Research Ltd
Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) – Drug Profiles
ABSK-011 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
AKR-001 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
derazantinib hydrochloride – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
EDP-317 – Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) – Dormant Products
Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) – Discontinued Products
Fibroblast Growth Factor Receptor 4 (CD334 or FGFR4 or EC 2.7.10.1) – Product Development Milestones
Featured News & Press Releases
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer

List of Tables
Number of Products under Development by Stage of Development, H2 2019
Number of Products under Development by Therapy Areas, H2 2019
Number of Products under Development by Indications, H2 2019
Number of Products under Development by Indications, H2 2019 (Contd..1), H2 2019
Number of Products under Development by Indications, H2 2019 (Contd..2), H2 2019
Number of Products under Development by Indications, H2 2019 (Contd..3), H2 2019
Number of Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019 (Contd..1), H2 2019
Products under Development by Companies, H2 2019 (Contd..2), H2 2019
Products under Development by Companies, H2 2019 (Contd..3), H2 2019
Products under Development by Companies, H2 2019 (Contd..4), H2 2019
Products under Development by Companies, H2 2019 (Contd..5), H2 2019
Products under Development by Companies, H2 2019 (Contd..6), H2 2019
Products under Development by Companies, H2 2019 (Contd..7), H2 2019
Products under Development by Companies, H2 2019 (Contd..8), H2 2019
Number of Products under Investigation by Universities/Institutes, H2 2019
Products under Investigation by Universities/Institutes, H2 2019
Number of Products by Stage and Mechanism of Actions, H2 2019
Number of Products by Stage and Route of Administration, H2 2019
Number of Products by Stage and Molecule Type, H2 2019
Pipeline by Abbisko Therapeutics Co Ltd, H2 2019
Pipeline by Akero Therapeutics Inc, H2 2019
Pipeline by ArQule Inc, H2 2019
Pipeline by Bayer AG, H2 2019
Pipeline by Blueprint Medicines Corp, H2 2019
Pipeline by Eddingpharm Inc, H2 2019
Pipeline by Eisai Co Ltd, H2 2019
Pipeline by Eli Lilly and Co, H2 2019
Pipeline by EUSOL Biotech Co Ltd, H2 2019
Pipeline by Everest Medicines Ltd, H2 2019
Pipeline by Genosco Inc, H2 2019
Pipeline by H3 Biomedicine Inc, H2 2019
Pipeline by ImmunoForge Co Ltd, H2 2019
Pipeline by Incyte Corp, H2 2019
Pipeline by InnoCare Pharma Ltd, H2 2019
Pipeline by Johnson & Johnson, H2 2019
Pipeline by NGM Biopharmaceuticals Inc, H2 2019
Pipeline by Principia Biopharma Inc, H2 2019
Pipeline by QED Therapeutics Inc, H2 2019
Pipeline by Vichem Chemie Research Ltd, H2 2019
Dormant Products, H2 2019
Dormant Products, H2 2019 (Contd..1), H2 2019
Discontinued Products, H2 2019

【掲載企業】

Abbisko Therapeutics Co Ltd
Akero Therapeutics Inc
ArQule Inc
Bayer AG
Blueprint Medicines Corp
Eddingpharm Inc
Eisai Co Ltd
Eli Lilly and Co
EUSOL Biotech Co Ltd
Everest Medicines Ltd
Genosco Inc
H3 Biomedicine Inc
ImmunoForge Co Ltd
Incyte Corp
InnoCare Pharma Ltd
Johnson & Johnson
NGM Biopharmaceuticals Inc
Principia Biopharma Inc
QED Therapeutics Inc
Vichem Chemie Research Ltd

【免責事項】
https://www.marketreport.jp/reports-disclaimer

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