1. Key Insights
2. Executive Summary of Dup15q Syndrome
3. Dup15q Syndrome Epidemiology Overview at a Glance
3.1. Epidemiology Share (%) Distribution of Dup15q Syndrome in 2017
3.2. Epidemiology Share (%) Distribution of Dup15q Syndrome in 2030
4. Disease Background and Overview: Dup15q Syndrome
4.1. Introduction
4.2. Signs, Symptoms and Characteristics
4.3. Chromosome 15
4.4. Chromosome Abnormalities Associated with Dup15q Syndrome
4.5. Genes Associated with Dup15q Syndrome
4.6. Quantitative Electrophysiological Biomarker of Dup15q Syndrome
4.7. Diagnosis
5. Epidemiology and Patient Population
5.1. Key Findings
5.2. KOL Views
5.3. Epidemiology Forecast Assumptions
5.4. Epidemiology Methodology
5.5. Total Prevalent Cases of Dup15q Syndrome in the 7MM
5.6. Total Diagnosed Prevalent Cases of Dup15q Syndrome in the 7MM
6. United States Epidemiology
6.1. Assumptions and Rationale
6.2. Total Prevalent Cases of Dup15q Syndrome in the United States
6.3. Total Diagnosed Prevalent Cases of Dup15q Syndrome in the United States
6.4. Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in the United States
7. EU5 Epidemiology
7.1. Assumptions and Rationale
7.2. Germany Epidemiology
7.2.1. Total Prevalent Cases of Dup15q Syndrome in Germany
7.2.2. Total Diagnosed Prevalent Cases of Dup15q Syndrome in Germany
7.2.3. Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Germany
7.3. France Epidemiology
7.3.1. Total Prevalent Cases of Dup15q Syndrome in France
7.3.2. Total Diagnosed Prevalent Cases of Dup15q Syndrome in France
7.3.3. Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in France
7.4. Italy Epidemiology
7.4.1. Total Prevalent Cases of Dup15q Syndrome in Italy
7.4.2. Total Diagnosed Prevalent Cases of Dup15q Syndrome in Italy
7.4.3. Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Italy
7.5. Spain Epidemiology
7.5.1. Total Prevalent Cases of Dup15q Syndrome in Spain
7.5.2. Total Diagnosed Prevalent Cases of Dup15q Syndrome in Spain
7.5.3. Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Spain
7.6. United Kingdom Epidemiology
7.6.1. Total Prevalent Cases of Dup15q Syndrome in the UK
7.6.2. Total Diagnosed Prevalent Cases of Dup15q Syndrome in the UK
7.6.3. Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in the UK
8. Japan Epidemiology
8.1. Assumptions and Rationale
8.2. Total Prevalent Cases of Dup15q Syndrome in Japan
8.3. Total Diagnosed Prevalent Cases of Dup15q Syndrome in Japan
8.4. Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Japan
9. Appendix
9.1. Bibliography
9.2. Report Methodology
10. DelveInsight Capabilities
11. Disclaimer
12. About DelveInsight
Table 1 Summary of Dup15q Syndrome, Epidemiology and Key Events (2017–2030)Table 2 Frequency of the main clinical characteristics of inv dup(15) or idic(15) syndrome
Table 3 Genomic testing used in 15q duplication and related disorders (Dup15q)
Table 4 Total Prevalent Cases of Dup15q Syndrome in the 7MM (2017–2030)
Table 5 Total Diagnosed Prevalent Cases of Dup15q Syndrome in the 7MM (2017–2030)
Table 6 Total Prevalent Cases of Dup15q Syndrome in the United States (2017–2030)
Table 7 Total Diagnosed Prevalent Cases of Dup15q Syndrome in the United States (2017–2030)
Table 8 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in the United States (2017–2030)
Table 9 Total Prevalent Cases of Dup15q Syndrome in Germany (2017–2030)
Table 10 Total Diagnosed Prevalent Cases of Dup15q Syndrome in Germany (2017–2030)
Table 11 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Germany (2017–2030)
Table 12 Total Prevalent Cases of Dup15q Syndrome in France (2017–2030)
Table 13 Total Prevalent Cases of Dup15q Syndrome in France (2017–2030)
Table 14 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in France (2017–2030)
Table 15 Total Prevalent Cases of Dup15q Syndrome in Italy (2017–2030)
Table 16 Total Diagnosed Prevalent Cases of Dup15q Syndrome in Italy (2017–2030)
Table 17 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Italy (2017–2030)
Table 18 Total Prevalent Cases of Dup15q Syndrome in Spain (2017–2030)
Table 19 Total Diagnosed Prevalent Cases of Dup15q Syndrome in Spain (2017–2030)
Table 20 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Spain (2017–2030)
Table 21 Total Prevalent Cases of Dup15q Syndrome in the UK (2017–2030)
Table 22 Total Diagnosed Prevalent Cases of Dup15q Syndrome in the UK (2017–2030)
Table 23 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in the UK (2017–2030)
Table 24 Total Prevalent Cases of Dup15q Syndrome in Japan (2017–2030)
Table 25 Total Diagnosed Prevalent Cases of Dup15q Syndrome in Japan (2017–2030)
Table 26 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Japan (2017–2030)
List of Figures
Figure 1 Signs, Symptoms and Characteristics
Figure 2 Chromosome 15
Figure 3 Chromosome abnormalities in Dup15q syndrome
Figure 4 Schematic representation of chromosome 15, showing the five recurrent breakpoints (BP), and the ~4 Mb segment that encompasses the PWS/AS critical region
Figure 5 Group averaged EEG topo plots
Figure 6 Diagnostic methods/techniques for Dup15q syndrome
Figure 7 United States KOL Views
Figure 8 United States and EU-5 KOL Views
Figure 9 United States KOL Views
Figure 10 KOL Views
Figure 11 Total Prevalent Cases of Dup15q Syndrome in the 7MM (2017–2030)
Figure 12 Total Diagnosed Prevalent Cases of Dup15q Syndrome in the 7MM (2017–2030)
Figure 13 Total Prevalent Cases of Dup15q Syndrome in the United States (2017–2030)
Figure 14 Total Diagnosed Prevalent Cases of Dup15q Syndrome in the United States (2017–2030)
Figure 15 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in the United States (2017–2030)
Figure 16 Total Prevalent Cases of Dup15q Syndrome in Germany (2017–2030)
Figure 17 Total Diagnosed Prevalent Cases of Dup15q Syndrome in Germany (2017–2030)
Figure 18 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Germany (2017–2030)
Figure 19 Total Prevalent Cases of Dup15q Syndrome in France (2017–2030)
Figure 20 Total Prevalent Cases of Dup15q Syndrome in France (2017–2030)
Figure 21 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in France (2017–2030)
Figure 22 Total Prevalent Cases of Dup15q Syndrome in Italy (2017–2030)
Figure 23 Total Diagnosed Prevalent Cases of Dup15q Syndrome in Italy (2017–2030)
Figure 24 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Italy (2017–2030)
Figure 25 Total Prevalent Cases of Dup15q Syndrome in Spain (2017–2030)
Figure 26 Total Diagnosed Prevalent Cases of Dup15q Syndrome in Spain (2017–2030)
Figure 27 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Spain (2017–2030)
Figure 28 Total Prevalent Cases of Dup15q Syndrome in the UK (2017–2030)
Figure 29 Total Diagnosed Prevalent Cases of Dup15q Syndrome in the UK (2017–2030)
Figure 30 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in the UK (2017–2030)
Figure 31 Total Prevalent Cases of Dup15q Syndrome in Japan (2017–2030)
Figure 32 Total Diagnosed Prevalent Cases of Dup15q Syndrome in Japan (2017–2030)
Figure 33 Type-specific Diagnosed Prevalent Cases of Dup15q Syndrome in Japan (2017–2030)
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