糖尿病同伴認知症治療薬の世界市場:疫学予測

◆英語タイトル:Dementia with Diabetes - Epidemiology Forecast to 2030
◆商品コード:DELV20JU189
◆発行会社(リサーチ会社):DelveInsight
◆発行日:2020年7月
◆ページ数:90
◆レポート言語:英語
◆レポート形式:PDF
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【レポートの概要】

DelveInsight’s ‘Dementia with Diabetes—Epidemiology Forecast–2030’ report delivers an in-depth understanding of the disease, historical and forecasted Dementia with Diabetes epidemiology in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Dementia with Diabetes Understanding
Dementia is a malady—usually of a chronic or progressive nature—in which there is deterioration in cognitive function (i.e., the ability to process thought).

It affects memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgment. The impairment in cognitive function is commonly accompanied and occasionally preceded, by deterioration in emotional control, social behavior, or motivation. Dementia develops as a result of a complex interplay of clinical and biological factors and is beset by multiple underlying pathological features. People with type 2 diabetes represent a substantial risk group for cognitive impairment and dementia caused by both Alzheimer’s disease dementia and vascular brain injury. Furthermore, type 2 diabetes increases the risk of mortality in patients who already have dementia, suggesting that targeted intervention at any point may improve health outcomes.

Diabetes is a condition in which the amount of glucose in the blood is too high due to defects in insulin secretion, action or both (American Diabetes Association, 2009). Insulin is a hormone produced by the pancreas gland, which controls glucose levels in the blood. If diabetes is not well-controlled or is diagnosed late, people with the condition can develop several disabling complications including blindness, kidney failure, foot ulcers, heart attacks, and stroke. There are two main types of diabetes which majorly includes type 1 and type 2 diabetes.

There are over 100 different types of dementia, but the most common type is Alzheimer’s, vascular dementia, Lewy body dementia, Parkinson’s, CJD, Pick’s disease, and alcohol-related dementia. Although many of the studies examined risk related to all-cause dementia, there is evidence that two specific subtypes, Alzheimer’s disease dementia and vascular dementia, are most strongly associated with type 2 diabetes. Early symptoms include forgetfulness, repetitiveness, short-term memory loss, and difficulty in finding the right words.

Dementia with Diabetes Epidemiology Perspective by DelveInsight
The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Prevalent Population of Dementia ,Age-specific prevalent population of dementia, Type-specific prevalent population of dementia, Severity-specific Prevalent Population of Alzheimer’s Dementia and Prevalence of Dementia (Alzheimer’s disease) with Diabetes a scenario of Dementia with Diabetes in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and United Kingdom) and Japan from 2017 to 2030.

Dementia with Diabetes Detailed Epidemiology Segmentation
The total prevalent cases of dementia in 7MM is 21,021,021 in 2017, which is expected to increase in the forecast period
Among the EU5, Germany accounts for the highest prevalent cases of dementia with diabetes followed by UK and France i.e., 173,957, 148,423 and 148,376 cases in 2017 which is estimated to increase in the forecast period.
According to DelveInsight, it is estimated that the type-specific prevalent cases of dementia in Alzheimers disease in the US were 5,796,827 in 2017 which is expected to increase by 2030.
The total prevalent cases of dementia in the UK were found to be 1,450,858 cases in 2017, which is expected to increase in the forecast period.
According to the analysis, in 2017, the higher aged population is commonly affected by dementia. As per the estimates, there were 267,546, 1,426,911, 4,013,188, and 3,210,550 cases of 50-64, 65–74, 75–84, and 85+ in 2017 in the US.
In US (2017), the estimated cases of type specific dementia for Alzheimer’s disease, vascular dementia, Lewy-body dementia, Fronto-temporal dementia, mixed dementia and others are 5,796,827, 1,337,729, 535,092, 89,182, 713,456 and 445,910.
In 2017, the total prevalent case of dementia with diabetes in Japan is expected to increase at a CAGR of 3.56% during the forecast period.
According to the analysis, mild cases accounts for 2,373,801 cases in 2017 followed by 2,484,520 moderate cases and 938,506 severe cases in the US respectively.
Scope of the Report
The report covers the descriptive overview of Dementia with Diabetes, explaining its causes, signs and symptoms, pathophysiology and currently available therapies.
The report provides insight into the 7MM historical and forecasted patient pool covering the United States, EU5 countries (Germany, France, Italy, Spain, and United Kingdom) and Japan.
The report assesses the disease risk and burden and highlights the unmet needs of Dementia with Diabetes.
The report provides the segmentation of the disease epidemiology for 7MM by Total Prevalent Cases of Dementia with Diabetes, Total Diagnosed and Treated Cases of Dementia with Diabetes.
Report Highlights
Eleven-Year Forecast of Dementia with Diabetes
7MM Coverage
Prevalent Population of Dementia
Age-specific prevalent population of dementia
Type-specific prevalent population of dementia
Severity-specific Prevalent Population of Alzheimer’s Dementia
Prevalence of Dementia (Alzheimer’s disease) with Diabetes
Key Questions Answered
What is the disease risk, burden and unmet needs of Dementia with Diabetes?
What is the historical Dementia with Diabetes patient pool in the United States, EU5 (Germany, France, Italy, Spain, and the UK) and Japan?
What would be the forecasted patient pool of Dementia with Diabetes at the 7MM level?
What will be the growth opportunities across the 7MM with respect to the patient population pertaining to Dementia with Diabetes?
Out of the countries mentioned above, which country would have the highest prevalent population of Dementia with Diabetes during the forecast period (2020–2030)?
At what CAGR the population is expected to grow across the 7MM during the forecast period (2020–2030)?
Reasons to buy
The Dementia with Diabetes report will allow the user to -

Develop business strategies by understanding the trends shaping and driving the 7MM Dementia with Diabetes market.
Quantify patient populations in the 7MM Dementia with Diabetes market to improve product design, pricing, and launch plans.
Organize sales and marketing efforts by identifying the specific type of Dementia with Diabetes that presents the best opportunities for Dementia with Diabetes therapeutics in each of the markets covered.
The Dementia with Diabetes epidemiology report and model were written and developed by Masters and PhD level epidemiologists.
The Dementia with Diabetes epidemiology model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over the 11-year forecast period using reputable sources.
Key Assessments
Patient Segmentation
Disease Risk and Burden
Risk of disease by the segmentation
Factors driving growth in a specific patient population
Geographies Covered
The United States
EU5 (Germany, France, Italy, Spain, and the United Kingdom)
Japan
Study Period: 2017–2030

【レポートの目次】

1 Key Insights

2 Executive Summary

3 SWOT Analysis

4 Dementia with Diabetes Market Overview at a Glance

4.1 Patient Share (%) Distribution of Dementia with Diabetes in 2017

4.2 Patient Share (%) Distribution of Dementia with Diabetes in 2030

5 Disease Background and Overview: Dementia with Diabetes

5.1 Introduction

5.2 Dementia

5.2.1 Types of Dementia

5.3 Dementia with Diabetes

5.4 Risk Factor

5.5 Signs and Symptoms of Dementia

5.6 Pathophysiology

5.7 Diagnosis

5.8 Diagnostic Guidelines

6 Recognized Establishments

7 Epidemiology and Patient Population

7.1 Key Findings

7.1 Total Prevalent Population of Dementia in the 7MM

7.2 Prevalence of Dementia (Alzheimer’s disease) with diabetes in the 7MM

7 3MM Epidemiology of Dementia with Diabetes

8. Assumption and Rationale

8.1 United States

8.1.1 Prevalent Population of Dementia in the United States

8.1.2 Age-specific prevalent population of dementia in the United States

8.1.3 Type-specific prevalent population of dementia in the United States

8.1.4 Severity Specific Prevalent Population of Alzheimer’s Dementia in the United States

8.1.5 Prevalence of Dementia (Alzheimer’s disease) with Diabetes in the United States

8.2 EU5 Countries

8.3 Germany

8.3.1 Prevalent Population of Dementia in Germany

8.3.2 Age-specific prevalent population of dementia in Germany

8.3.3 Type-specific prevalent population of dementia in Germany

8.3.4 Severity Specific Prevalent Population of Alzheimer’s Dementia in Germany

8.3.5 Prevalence of Dementia (Alzheimer’s disease) with Diabetes in Germany

8.4 France

8.4.1 Prevalent Population of Dementia in France

8.4.2 Age-specific prevalent population of dementia in France

8.4.3 Type-specific prevalent population of dementia in France

8.4.4 Severity Specific Prevalent Population of Alzheimer’s Dementia in France

8.4.5 Prevalence of Dementia (Alzheimer’s disease) with Diabetes in France

8.5 Italy

8.5.1 Prevalent Population of Dementia in Italy

8.5.2 Age-specific prevalent population of dementia in Italy

8.5.3 Type-specific prevalent population of dementia in Italy

8.5.4 Severity Specific Prevalent Population of Alzheimer’s Dementia in Italy

8.5.5 Prevalence of Dementia (Alzheimer’s disease) with Diabetes in Italy

8.6 Spain

8.6.1 Prevalent Population of Dementia in Spain

8.6.2 Age-specific prevalent population of dementia in Spain

8.6.3 Type-specific prevalent population of dementia in Spain

8.6.4 Severity Specific Prevalent Population of Alzheimer’s Dementia in Spain

8.6.5 Prevalence of Dementia (Alzheimer’s disease) with Diabetes in Spain

8.7 United Kingdom

8.7.1 Prevalent Population of Dementia in the United Kingdom

8.7.2 Age-specific prevalent population of dementia in the United Kingdom

8.7.3 Type-specific prevalent population of dementia in the United Kingdom

8.7.4 Severity Specific Prevalent Population of Alzheimer’s Dementia in the United Kingdom

8.7.5 Prevalence of Dementia (Alzheimer’s disease) with Diabetes in the United Kingdom

8.8 Japan

8.8.1 Prevalent Population of Dementia in Japan

8.8.2 Age-specific prevalent population of dementia in Japan

8.8.3 Type-specific prevalent population of dementia in Japan

8.8.4 Severity Specific Prevalent Population of Alzheimer’s Dementia in Japan

8.8.5 Prevalence of Dementia (Alzheimer’s disease) with Diabetes in Japan

9 Appendix

10 DelveInsight Capabilities

11 Disclaimer

12 About DelveInsight

Table 1: Summary of Dementia with Diabetes Market, Epidemiology and Key Events (2017–2030)

Table 2: Issues for people with dementia/diabetes who develop diabetes/dementia

Table 3: Guideline recommendations for key clinical outcomes for older people with diabetes from Diabetes Canada (DC), American Diabetes Association (ADA) and International Diabetes Federation (IDF)

Table 4: Total Prevalent Population of dementia in the 7MM Countries (2017–2030)

Table 5: Prevalence of Dementia (Alzheimer's disease) with diabetes in the 7MM Countries (2017–2030)

Table 6: Prevalent Population of dementia in the United States (2017–2030)

Table 7: Age-specific prevalent population of dementia in the United States (2017–203

Table 8: Type-specific prevalent population of dementia in the United States (2017–2030)

Table 9: Severity Specific Prevalent Population of Alzheimer's Dementia in the United States (2017–2030)

Table 10: Prevalence of Dementia (Alzheimer's disease) with Diabetes in the United States (2017–2030)

Table 11: Prevalent Population of dementia in Germany (2017–2030)

Table 12: Age-specific prevalent population of dementia in Germany (2017–2030)

Table 13: Type-specific prevalent population of dementia in Germany (2017–2030)

Table 14: Severity Specific Prevalent Population of Alzheimer's Dementia in Germany (2017–2030)

Table 15: Prevalence of Dementia (Alzheimer's disease) with Diabetes in Germany (2017–2030)

Table 16: Prevalent Population of dementia in France (2017–2030)

Table 17: Age-specific prevalent population of dementia in France (2017–2030)

Table 18: Type-specific prevalent population of dementia in France (2017–2030)

Table 19: Severity Specific Prevalent Population of Alzheimer's Dementia in France (2017–2030)

Table 20: Prevalence of Dementia (Alzheimer's disease) with Diabetes in France (2017–2030)

Table 21: Prevalent Population of dementia in Italy (2017–2030)

Table 22: Age-specific prevalent population of dementia in Italy (2017–2030)

Table 23: Type-specific prevalent population of dementia in Italy (2017–2030)

Table 24: Severity Specific Prevalent Population of Alzheimer's Dementia in Italy (2017–2030)

Table 25: Prevalence of Dementia (Alzheimer's disease) with Diabetes in Italy (2017–2030)

Table 26: Prevalent Population of dementia in Spain (2017–2030)

Table 27: Age-specific prevalent population of dementia in Spain (2017–2030)

Table 28: Type-specific prevalent population of dementia in Spain (2017–2030)

Table 29: Severity Specific Prevalent Population of Alzheimer's Dementia in Spain (2017–2030)

Table 30: Prevalence of Dementia (Alzheimer's disease) with Diabetes in Spain (2017–2030)

Table 31: Prevalent Population of dementia in the United Kingdom (2017–2030)

Table 32: Age-specific prevalent population of dementia in the United Kingdom (2017–2030)

Table 33: Type-specific prevalent population of dementia in the United Kingdom (2017–2030)

Table 34: Severity Specific Prevalent Population of Alzheimer's Dementia in the United Kingdom (2017–2030)

Table 35: Prevalence of Dementia (Alzheimer's disease) with Diabetes in the United Kingdom (2017–2030)

Table 36: Prevalent Population of dementia in Japan (2017–2030)

Table 37: Age-specific prevalent population of dementia in Japan (2017–2030)

Table 38: Type-specific prevalent population of dementia in Japan (2017–2030)

Table 39: Severity Specific Prevalent Population of Alzheimer's Dementia in Japan (2017–2030)

Table 40: Prevalence of Dementia (Alzheimer's disease) with Diabetes in Japan (2017–2030)

List of Figures

Figure 1: Dementia with Diabetes SWOT Analysis

Figure 2: Types of Dementia

Figure 3: Major Types of Dementia

Figure 4: Risk factor of Dementia

Figure 5: Signs and Symptoms of Dementia

Figure 6: Pathophysiologic factors associated with dementia and diabetes in the elderly

Figure 7: The potential role of insulin in the pathogenesis of dementia

Figure 8: Proposed pathophysiological mechanisms linking diabetes to changes in the brain and dementia

Figure 9: Total Prevalent Population of dementia in the 7MM Countries (2017–2030)

Figure 10: Prevalence of Dementia (Alzheimer's disease) with diabetes in the 7MM Countries (2017–2030)

Figure 11: Prevalent Population of dementia in the United States (2017–2030)

Figure 12: Age-specific prevalent population of Dementia in the United States (2017–2030)

Figure 13: Type-specific prevalent population of dementia in the United States (2017–2030)

Figure 14: Severity Specific Prevalent Population of Alzheimer's Dementia in the United States (2017–2030)

Figure 15: Prevalence of Dementia (Alzheimer's disease) with Diabetes in the United States (2017–2030)

Figure 16: Prevalent Population of dementia in Germany (2017–2030)

Figure 17: Age-specific prevalent population of Dementia in Germany (2017–2030)

Figure 18: Type-specific prevalent population of dementia in Germany (2017–2030)

Figure 19: Severity Specific Prevalent Population of Alzheimer's Dementia in Germany (2017–2030)

Figure 20: Prevalence of Dementia (Alzheimer's disease) with Diabetes in Germany (2017–2030)

Figure 21: Prevalent Population of dementia in France (2017–2030)

Figure 22: Age-specific prevalent population of Dementia in France (2017–2030)

Figure 23: Type-specific prevalent population of dementia in France (2017–2030)

Figure 24: Severity Specific Prevalent Population of Alzheimer's Dementia in France (2017–2030)

Figure 25: Prevalence of Dementia (Alzheimer's disease) with Diabetes in France (2017–2030)

Figure 26: Prevalent Population of dementia in Italy (2017–2030)

Figure 27: Age-specific prevalent population of Dementia in Italy (2017–2030)

Figure 28: Type-specific prevalent population of dementia in Italy (2017–2030)

Figure 29: Severity Specific Prevalent Population of Alzheimer's Dementia in Italy (2017–2030)

Figure 30: Prevalence of Dementia (Alzheimer's disease) with Diabetes in Italy (2017–2030)

Figure 31: Prevalent Population of dementia in Spain (2017–2030)

Figure 32: Age-specific prevalent population of Dementia in Spain (2017–2030)

Figure 33: Type-specific prevalent population of dementia in Spain (2017–2030)

Figure 34: Severity Specific Prevalent Population of Alzheimer's Dementia in Italy (2017–2030)

Figure 35: Prevalence of Dementia (Alzheimer's disease) with Diabetes in Spain (2017–2030)

Figure 36: Prevalent Population of dementia in the United Kingdom (2017–2030)

Figure 37: Age-specific prevalent population of Dementia in the United Kingdom (2017–2030)

Figure 38: Type-specific prevalent population of dementia in the United Kingdom (2017–2030)

Figure 39: Severity Specific Prevalent Population of Alzheimer's Dementia in the United Kingdom (2017–2030)

Figure 40: Prevalence of Dementia (Alzheimer's disease) with Diabetes in the United Kingdom (2017–2030)

Figure 41: Prevalent Population of dementia in Japan (2017–2030)

Figure 42: Age-specific prevalent population of Dementia in Japan (2017–2030)

Figure 43: Type-specific prevalent population of dementia in Japan (2017–2030)

Figure 44: Severity Specific Prevalent Population of Alzheimer's Dementia in Japan (2017–2030)

Figure 45: Prevalence of Dementia (Alzheimer's disease) with Diabetes in Japan (2017–2030)

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